The matrix found in Week One of the student website is intended to assist you in organizing the information contained in these sources. Consider the types of marketing messages that these information sources may contain and the reliability of the marketing message. Following the provided example, identify three examples of your own. Health Care Marketing Information Matrix grading criteria located on the student website.
Background A tumor marker is a substance such as a protein, antigen or hormone in the body that may indicate the presence of cancer. Generally, these markers are specific to certain types of cancer and can be detected in blood, urine and tissue samples. The body may produce the marker in response to cancer or the tumor itself may produce the marker.
The detection of tumor markers may be used to determine a diagnosis or as an indicator of disease cancer progression. It can also be used to document clinical response to treatment. Tumor markers are normally produced in low quantities by cells in the body.
Detection of a higher-than-normal serum level by radioimmunoassay or immunohistochemical techniques Week 1 hcs 490 matrix indicates the presence of a certain type of cancer. Currently, the main use of tumor mfarkers is to assess a cancer's response to treatment and to check for recurrence.
In some types of cancer, tumor marker levels may reflect the extent or stage of the disease and can be useful in predicting how well the disease will respond to treatment.
A decrease or return to normal in the level of a tumor marker may indicate that the cancer has responded favorably to therapy. If the tumor marker level rises, it may indicate that the cancer is spreading.
Finally, measurements of tumor marker levels may be used after treatment has ended as a part of follow-up care to check for recurrence. However, in many cases the literature states that measurements of tumor marker levels alone are insufficient to diagnose cancer for the following reasons: High levels of B2M are an indicator of certain kinds of cancer, including chronic lymphocytic leukemia, non-Hodgkin's lymphoma and multiple myeloma or kidney disease; Beta Human Chorionic Gonadotropin beta HCG — A type of tumor marker that may be found in higher than normal amounts in individuals with some types of cancer; Calcitonin — Hormone secreted by the thyroid that lowers blood calcium; Calretinin — A calcium-binding protein that is used as a marker in the evaluation of lung cancer and other diseases.
Chromogranin A — A protein found inside neuroendocrine cells, which releases chromogranin A and other hormones into the blood. Chromogranin A may be found in higher than normal amounts in individuals with certain neuroendocrine tumors, small cell lung cancer, prostate cancer and other conditions Guanylyl cyclase c GCC — An enzyme that may be expressed only in the cells that line the intestine from the duodenum to the rectum.
Inhibin — One of two hormones designated inhibin-A and inhibin-B secreted by the gonads by Sertoli cells in the male and the granulosa cells in the female and inhibits the production of follicle-stimulating hormone FSH by the pituitary gland; Lactate Dehydrogenase LDH — Marker used to monitor treatment of testicular cancer; Mucin-1 MUC-1 — Carbohydrate antigen elevated in individuals with tumors of the breast, ovary, lung and prostate as well as other disorders; Napsin A — Protein used as a marker in the evaluation of lung cancer; Prealbumin — Marker of nutritional status and a sensitive indicator of protein synthesis.
Levels of PSA in the blood often increase in men with prostate cancer. Thyroglobulin — Protein found in the thyroid gland. Some thyroglobulin can be found in the blood and this amount may be measured after thyroid surgery to determine whether thyroid cancer has recurred; Thyroid Transcription Factor-1 TTF-1 — A protein that is used as a tumor marker in the evaluation of lung cancer; Transferrin — A protein in blood plasma that carries iron derived from food intake to the liver, spleen and bone marrow.
Tumors may be evaluated with histology, which involves examination of the structure, especially the microscopic structure, of organic tissues. Methods of detecting tumor markers include, but are not limited to: Immunohistochemical IHC Analysis — Laboratory process of detecting an organism in tissues with antibodies.
Gene mutation testing can purportedly be used to find somatic mutations in cancerous cells that are not inherited. Some examples of genes that may have somatic mutations include: Individualized molecular tumor profiling is a laboratory method of testing a panel of tumor markers, which may include genetic as well as biochemical markers, to establish a personalized molecular profile of a tumor to recommend treatment options.
Next-generation sequence NGS tests use select genes to purportedly identify molecular growth drivers for improved risk stratification and targeted therapies. Liquid biopsy refers to serum testing for DNA fragments that are shed by cancer cells and released into the bloodstream.
The laboratory performs an algorithmic analysis using the results of the assays and sometimes other information, such as sex and age and converts the information into a numeric score, which is conveyed on a laboratory report.
Generally, MAAAs are exclusive to a single laboratory which owns the algorithm. MAAAs have been proposed for the evaluation of pelvic masses, including assisting in the determination of referral for surgery to a gynecologic oncologist or to a general surgeon.
Topographic genotyping eg, PathFinderTG is a test that examines a panel of 15 to 20 genetic markers in tissue biopsy or other tissue specimens to purportedly aid in the determination of indeterminate or equivocal cancer diagnoses. Elevated levels of Prostate-Specific Antigen PSA may also be found in the blood of men with benign prostate conditions, such as prostatitis and benign prostatic hyperplasia BPH.
While PSA does not allow distinction between benign prostate conditions and cancer, an elevated PSA level may indicate that other tests are necessary to determine whether cancer is present. PSA levels have been shown to be useful in monitoring the effectiveness of prostate cancer treatment, and in checking for recurrence after treatment has ended.
Use of PSA for screening remains very controversial. Although researchers are in the process of studying the value of PSA along with digital rectal exams for routine screening of men ages 55 to 74 for prostate cancer; and the literature does not show at this time whether using PSA to screen for prostate cancer actually does reduce the number of deaths caused by this cancer.
The American Cancer Society recommends clinicians and patients consider screening with PSA and digital rectal exam for African American men and men with familial tendency age 40 or older and all men age 50 or older.
The guidelines state that "[c]urrent evidence shows that PSA kinetics does not reliably predict disease stability or reclassification to higher risk state. There was conflicting evidence whether PSA is a good predictor of disease progression or reclassification.HCS Week 1 Individual Assignment Health Care Marketing Information Matrix There are a variety of information sources that may be used by consumers to obtain information relating to the marketing of health care products and services.
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The matrix found in Week One of the student website is intended to assist you in organizing the information contained in these sources. Consider the types of marketing messages that these information sources may contain and the reliability of the marketing message.
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Search the world's information, including webpages, images, videos and more. Google has many special features to help you find exactly what you're looking for. Week 1 Hcs Matrix. University of Phoenix Material Health Care Marketing Information Matrix There are a variety of information sources that may be used by consumers to obtain information relating to the marketing of health care products and services.